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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
E2F5
All Species:
23.94
Human Site:
Y172
Identified Species:
37.62
UniProt:
Q15329
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15329
NP_001077057.1
346
37610
Y172
S
I
N
N
R
F
S
Y
V
T
H
E
D
I
C
Chimpanzee
Pan troglodytes
XP_511025
426
45548
Y158
V
Q
N
S
C
L
A
Y
V
T
H
E
D
I
C
Rhesus Macaque
Macaca mulatta
XP_001094919
346
37697
Y172
S
I
N
N
R
F
S
Y
V
T
H
E
D
I
C
Dog
Lupus familis
XP_853833
304
33793
D136
F
S
Y
V
T
H
E
D
I
C
N
C
F
N
G
Cat
Felis silvestris
Mouse
Mus musculus
Q61502
335
36766
Y162
S
I
N
N
R
F
S
Y
V
T
H
E
D
I
C
Rat
Rattus norvegicus
Q62814
300
33206
S135
V
T
H
E
D
I
C
S
C
F
N
G
D
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517985
227
25092
E61
R
F
S
Y
V
T
H
E
D
I
C
N
C
F
N
Chicken
Gallus gallus
Q90977
403
43534
Y222
P
S
N
Q
H
A
A
Y
V
T
C
Q
D
L
R
Frog
Xenopus laevis
NP_001086706
375
40890
Y135
V
Q
N
T
G
L
A
Y
L
N
H
E
D
I
C
Zebra Danio
Brachydanio rerio
NP_998597
393
42365
T136
N
S
P
L
A
Y
V
T
H
Q
D
L
C
N
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27368
805
87442
Y372
E
N
S
G
G
M
A
Y
V
T
Q
N
D
L
L
Honey Bee
Apis mellifera
XP_624285
300
34327
D135
H
A
Y
I
T
Y
E
D
V
K
E
N
F
T
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799123
356
39484
Y174
G
P
D
N
Q
K
R
Y
M
V
H
L
K
S
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130952
446
48668
T252
N
Q
K
W
L
Y
V
T
E
E
D
I
K
S
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565831
483
52579
F286
E
K
N
Q
K
W
L
F
V
T
E
E
D
I
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.8
97.9
78.9
N.A.
88.1
82.6
N.A.
57.2
33
58.1
56.2
N.A.
20.6
41
N.A.
51.9
Protein Similarity:
100
62.2
98.5
82.6
N.A.
90.1
84.3
N.A.
60.6
49.6
68.8
66.1
N.A.
29.6
55.2
N.A.
65.1
P-Site Identity:
100
60
100
0
N.A.
100
6.6
N.A.
0
33.3
46.6
6.6
N.A.
26.6
6.6
N.A.
20
P-Site Similarity:
100
73.3
100
13.3
N.A.
100
20
N.A.
6.6
53.3
60
20
N.A.
46.6
13.3
N.A.
40
Percent
Protein Identity:
N.A.
31.3
N.A.
28.1
N.A.
N.A.
Protein Similarity:
N.A.
45
N.A.
41.2
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
40
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
7
7
27
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
7
0
7
0
7
7
14
7
14
0
40
% C
% Asp:
0
0
7
0
7
0
0
14
7
0
14
0
60
0
7
% D
% Glu:
14
0
0
7
0
0
14
7
7
7
14
40
0
0
0
% E
% Phe:
7
7
0
0
0
20
0
7
0
7
0
0
14
7
7
% F
% Gly:
7
0
0
7
14
0
0
0
0
0
0
7
0
0
7
% G
% His:
7
0
7
0
7
7
7
0
7
0
40
0
0
0
0
% H
% Ile:
0
20
0
7
0
7
0
0
7
7
0
7
0
40
0
% I
% Lys:
0
7
7
0
7
7
0
0
0
7
0
0
14
0
7
% K
% Leu:
0
0
0
7
7
14
7
0
7
0
0
14
0
14
20
% L
% Met:
0
0
0
0
0
7
0
0
7
0
0
0
0
0
0
% M
% Asn:
14
7
47
27
0
0
0
0
0
7
14
20
0
14
7
% N
% Pro:
7
7
7
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
20
0
14
7
0
0
0
0
7
7
7
0
0
0
% Q
% Arg:
7
0
0
0
20
0
7
0
0
0
0
0
0
0
7
% R
% Ser:
20
20
14
7
0
0
20
7
0
0
0
0
0
14
0
% S
% Thr:
0
7
0
7
14
7
0
14
0
47
0
0
0
14
0
% T
% Val:
20
0
0
7
7
0
14
0
54
7
0
0
0
0
0
% V
% Trp:
0
0
0
7
0
7
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
14
7
0
20
0
54
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _